Epidural clonidine used as an adjunct to area anesthetics has three unique mechanisms of action. First, the stimulation of alpha-2-receptors inside the dorsal horn minimizes ache transmission. Secondly, clonidine can cause regional vasoconstriction that restrictions vascular elimination of regional epidural anesthetics. Clonidine treats substantial blood pressure by stimulating α2 https://ez-bookmarking.com/story19778582/the-2-minute-rule-for-onolidine