Abstract Background Glioma initiating cells (GICs). also known as glioma stem cells (GSCs). play an important role in the progression and recurrence of glioblastoma multiforme (GBM) due to their potential for self-renewal. multiple differentiation and tumor initiation. https://www.alarecre.com/American-Flag-Color-Block-iPhone-14-Waterproof-Case-p12619/